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Table 1 Fluorescent-labeled mice for intravital multiphoton imaging in bone

From: Intravital imaging of orthotopic and ectopic bone

Target gene/promoter Fluorescence (color) Labeled cells Report
(development)
Report
intravital imaging)
CX3CR1 EGFP (green) Macrophage Jung et al. Mol. Cell. Biol. (2000) [16]. Ishii et al. Nature (2009) [17].
V-ATPase a3 subunit promoter GFP (green) Macrophage Sun-Wada et al. J Cell Sci. (2009) [14]. Kikuta et al. J. Clin. Invest. (2013) [12].
TRAP (exon 2) tdTomato (red) Osteoclasts Kikuta et al. J. Clin. Invest. (2013) [12]. Kikuta et al. J. Clin. Invest. (2013) [12]. Furuya et al. Nat. Commun. (2018) [13].
Rat COL1A1 promoter (2.3 kb) ECFP (cyan) Osteoblasts Furuya et al. Nat. Commun. (2018) [13]. Furuya et al. Nat. Commun. (2018) [13]. Hashimoto et al. Sci Rep. (2020) [15].
Rat COL1A1 promoter (2.3 kb) GFP (green) Osteoblasts Kalajzic et al. J. Bone Miner. Res. (2002) [18]. Kalajzic et al. J. Bone Miner. Res. (2002) [15].
Villa et al. Tissue Eng Part C Methods. (2013) [19].
Huang C, et al. J Bone Miner Res. (2015).
[20]
  1. CX3CR1 C-X3-C motif chemokine receptor 1, EGFP enhanced green fluorescent protein, V-ATPase V-type H+-ATPase, GFP green fluorescent protein, TRAP tartrate-resistant acid phosphatase, COL1A1 collagen type 1 alpha 1, ECFP enhanced cyan fluorescent protein
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