Table 1 Disease-susceptible SNPs in super-enhancers
From: Critical roles of super-enhancers in the pathogenesis of autoimmune diseases
| Autoimmune diseases | Affected cell types | Disease-sensitive SNPs (n) | SNPs within SE (n) | Ref. |
|---|---|---|---|---|
| Rheumatoid arthritis | CD4+ T | 101 | 27 | [40, 41] |
| Systemic lupus erythematosus | N.D. | over 60 | N.D. | [42, 43] |
| Multiple sclerosis | CD4+ T | 87 | 36 | [41, 44] |
| Systemic sclerosis | N.D. | 27 | N.D. | [45] |
| Graves’ disease | N.D. | 101 | N.D. | [46] |
| Behcet’s disease | N.D. | 19 | N.D. | [47] |
| Atopic dermatitis | N.D. | 31 | N.D. | [48] |
| Vitiligo | N.D. | over 30 | N.D. | [49] |
| Inflammatory bowel disease | CD4+ T | 216 | 91 | [41, 50] |